Centrosome-associated protein ALMS1

Definition:

Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells.

References:

[1]. Susanne Graser, et al. Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol. 2007 Oct 22;179(2):321-30. [Content Brief]

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