Clonal hematopoiesis of indeterminate potential (CHIP)

Definition:

Clonal hematopoiesis of indeterminate potential (CHIP) is a new entity where somatic mutations are found in blood or bone marrow cells, but no other criteria for hematologic neoplasia are met.

References:

[1]. Marnell CS, et al. Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease. J Mol Cell Cardiol. 2021 Dec;161:98-105. [Content Brief]

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