Contactin-associated protein-like 2

Definition:

Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.

References:

[1]. Lingfeng Meng, et al. NLR-1/CASPR Anchors F-Actin to Promote Gap Junction Formation. Dev Cell. 2020 Dec 7;55(5):574-587.e3. [Content Brief]

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