CREB3 regulatory factor

Definition:

Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.

References:

[1]. Timothy E Audas, et al. A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response. Mol Cell Biol. 2008 Jun;28(12):3952-66. [Content Brief]

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