CXADR-like membrane protein

Definition:

May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.

References:

[1]. Elisabeth Raschperger, et al. CLMP, a novel member of the CTX family and a new component of epithelial tight junctions. J Biol Chem. 2004 Jan 2;279(1):796-804. [Content Brief]

[2]. Christine S Van Der Werf, et al. CLMP is required for intestinal development, and loss-of-function mutations cause congenital short-bowel syndrome. Gastroenterology. 2012 Mar;142(3):453-462.e3. [Content Brief]

[3]. Jun Eguchi, et al. Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity. Biochem J. 2005 Apr 15;387(Pt 2):343-53. [Content Brief]

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