Cyclic guanosine monophosphate (cGMP)

Definition:

Cyclic guanosine monophosphate (cGMP) is an important intracellular second messenger that mediates multiple tissue and cellular responses. The cGMP pathway is a key element in the pathophysiology of the heart.

References:

[1]. Rakesh C Kukreja, et al. Cyclic guanosine monophosphate signaling and phosphodiesterase-5 inhibitors in cardioprotection. J Am Coll Cardiol. 2012 May 29;59(22):1921-7. [Content Brief]

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