cyclophosphamide (CYP)

Definition:

Cyclophosphamide (CYP)is a widely utilized antineoplastic drugs, the potent immunosuppressive agent, and the most commonly used drug in blood and marrow transplantation (BMT). Cyclophosphamide (CYP)shows unique metabolism and inactivation by aldehyde dehydrogenase to exhibit distinct cytotoxic properties.

References:

[1]. Emadi A, Jones RJ, Brodsky RA. Cyclophosphamide and cancer: golden anniversary. Nat Rev Clin Oncol. 2009 Nov;6(11):638-47. [Content Brief]

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