Death-inducer obliterator 1

Definition:

Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development.; [Isoform 2]: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes.

References:

[1]. Agnes Fütterer, et al. Dido gene expression alterations are implicated in the induction of hematological myeloid neoplasms. J Clin Invest. 2005 Sep;115(9):2351-62. [Content Brief]

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