Deoxyribose-phosphate aldolase

Definition:

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.

References:

[1]. Lisa Salleron, et al. DERA is the human deoxyribose phosphate aldolase and is involved in stress response. Biochim Biophys Acta. 2014 Dec;1843(12):2913-25. [Content Brief]

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