Differentially expressed in FDCP 6 homolog
Definition:
References:
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[1]. Sanjay Gupta, et al. Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system. Hum Immunol. 2003 Apr;64(4):389-401. [Content Brief]
[2]. Nina K Serwas, et al. Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis. Nat Commun. 2019 Jul 15;10(1):3106. [Content Brief]
[3]. Konstantinos J Mavrakis, et al. DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA. Exp Cell Res. 2004 Apr 1;294(2):335-44. [Content Brief]
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