DNA topoisomerase 2-alpha
Definition:
References:
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[1]. Jessica P Wyles, et al. Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1. Nucleic Acids Res. 2007;35(12):4076-85. [Content Brief]
[2]. Mahesh Ramamoorthy, et al. RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression. Nucleic Acids Res. 2012 Feb;40(4):1621-35. [Content Brief]
[3]. Elizabeth A Williamson, et al. The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation. Nucleic Acids Res. 2008 Oct;36(18):5822-31. [Content Brief]
[4]. Sanghwa Lee, et al. DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2925-30. [Content Brief]
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