DNA topoisomerase II (topo II)

Definition:

DNA topoisomerase II (topo II) are essential and ubiquitous enzymes that perform important intracellular roles in chromosome condensation and segregation, and in regulating DNA supercoiling.

References:

[1]. Collins TR, et al. Analysis of the eukaryotic topoisomerase II DNA gate: a single-molecule FRET and structural perspective. Nucleic Acids Res. 2009 Feb;37(3):712-20. [Content Brief]

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