Dual specificity tyrosine-phosphorylation-regulated kinase 1B
Definition:
References:
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[1]. Ali R Keramati, et al. A form of the metabolic syndrome associated with mutations in DYRK1B. N Engl J Med. 2014 May 15;370(20):1909-1919. [Content Brief]
[2]. Chao Dong, et al. A DYRK1B-dependent pathway suppresses rDNA transcription in response to DNA damage. Nucleic Acids Res. 2021 Feb 22;49(3):1485-1496. [Content Brief]
[3]. Seunghwan Lim, et al. Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha. J Biol Chem. 2002 Jul 12;277(28):25040-6. [Content Brief]
[4]. K Lee, et al. Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells. Cancer Res. 2000 Jul 1;60(13):3631-7. [Content Brief]
[5]. Chao Dong, et al. Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17019-17030. [Content Brief]
[6]. Yonglong Zou, et al. Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran-binding protein M. J Biol Chem. 2003 Dec 5;278(49):49573-81. [Content Brief]
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