Dynamin-2
Definition:
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity).
References:
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[1]. Heather M Thompson, et al. The large GTPase dynamin associates with the spindle midzone and is required for cytokinesis. Curr Biol. 2002 Dec 23;12(24):2111-7. [Content Brief]
[2]. Man Lung Yeung, et al. Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. Cell. 2021 Apr 15;184(8):2212-2228.e12. [Content Brief]
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