E3 ubiquitin-protein ligase Praja-1

Definition:

Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.

References:

[1]. Ping Yu, et al. PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain. Genomics. 2002 Jun;79(6):869-74. [Content Brief]

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