E3 ubiquitin-protein ligase RNF13
Definition:
References:
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[1]. Qiang Zhang, et al. RNF13: a novel RING-type ubiquitin ligase over-expressed in pancreatic cancer. Cell Res. 2009 Mar;19(3):348-57. [Content Brief]
[2]. Jesper R van Dijk, et al. Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization. Biochem J. 2014 Apr 1;459(1):27-36. [Content Brief]
[3]. Simon Edvardson, et al. Heterozygous RNF13 Gain-of-Function Variants Are Associated with Congenital Microcephaly, Epileptic Encephalopathy, Blindness, and Failure to Thrive. Am J Hum Genet. 2019 Jan 3;104(1):179-185. [Content Brief]
[4]. Muhammad Arshad, et al. RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway. J Biol Chem. 2013 Mar 22;288(12):8726-8736. [Content Brief]
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