Ectonucleoside triphosphate diphosphohydrolase 3

Definition:

Has a threefold preference for the hydrolysis of ATP over ADP.

References:

[1]. T M Smith, et al. Mutagenesis of two conserved tryptophan residues of the E-type ATPases: inactivation and conversion of an ecto-apyrase to an ecto-NTPase. Biochemistry. 1999 May 4;38(18):5849-57. [Content Brief]

[2]. F Yang, et al. Site-directed mutagenesis of human nucleoside triphosphate diphosphohydrolase 3: the importance of residues in the apyrase conserved regions. Biochemistry. 2001 Apr 3;40(13):3943-50. [Content Brief]

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