Exchange proteins directly activated by cAMP (EPACs)

Definition:

Exchange proteins directly activated by cAMP (EPACs) are a family of signalling proteins that bind cAMP and activate the small Ras-related monomeric G proteins Rap1 and Rap2.

References:

[1]. Purves GI, et al. Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels. J Physiol. 2009 Jul 15;587(Pt 14):3639-50. [Content Brief]

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