F-box/LRR-repeat protein 19

Definition:

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity). Binds to DNA containing unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides.

References:

[1]. Chao Xu, et al. DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure. 2018 Jan 2;26(1):85-95.e3. [Content Brief]

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