F-box only protein 4
Definition:
References:
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[1]. C Cenciarelli, et al. Identification of a family of human F-box proteins. Curr Biol. 1999 Oct 21;9(20):1177-9. [Content Brief]
[2]. Zhixiong Zeng, et al. Structural basis of selective ubiquitination of TRF1 by SCFFbx4. Dev Cell. 2010 Feb 16;18(2):214-25. [Content Brief]
[3]. Yunfeng Li, et al. Structural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligase. J Biol Chem. 2010 Apr 30;285(18):13896-906. [Content Brief]
[4]. Tae Ho Lee, et al. The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance. J Biol Chem. 2006 Jan 13;281(2):759-68. [Content Brief]
[5]. Olena Barbash, et al. Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer. Cancer Cell. 2008 Jul 8;14(1):68-78. [Content Brief]
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