F-box/WD repeat-containing protein 7

[1]. K Yalla, et al. FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Mol Psychiatry. 2018 May;23(5):1278-1286. [Content Brief]

[2]. Nikita Popov, et al. The ubiquitin-specific protease USP28 is required for MYC stability. Nat Cell Biol. 2007 Jul;9(7):765-74. [Content Brief]

[3]. Xuan Zhao, et al. Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation. Cell. 2016 Jun 16;165(7):1644-1657. [Content Brief]

[4]. Nikita Popov, et al. Fbw7 and Usp28 regulate myc protein stability in response to DNA damage. Cell Cycle. 2007 Oct 1;6(19):2327-31. [Content Brief]

[5]. Abdolrahman S Nateri, et al. The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling. Science. 2004 Feb 27;303(5662):1374-8. [Content Brief]

[6]. Qiang Zhang, et al. FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4. Mol Cell. 2016 Feb 4;61(3):419-433. [Content Brief]

[7]. Masayoshi Yada, et al. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J. 2004 May 19;23(10):2116-25. [Content Brief]

[8]. Veronika Reiterer, et al. The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function. EMBO J. 2017 Feb 1;36(3):260-273. [Content Brief]

[9]. G Wu, et al. SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. Mol Cell Biol. 2001 Nov;21(21):7403-15. [Content Brief]

[10]. Hidefumi Fukushima, et al. NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis. Mol Cell. 2017 Nov 16;68(4):645-658.e5. [Content Brief]

[11]. Jinhe Li, et al. SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production. J Neurochem. 2002 Sep;82(6):1540-8. [Content Brief]

[12]. Xiao-Xin Sun, et al. The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3734-9. [Content Brief]

[13]. H Strohmaier, et al. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature. 2001 Sep 20;413(6853):316-22. [Content Brief]

[14]. Sang-Hyun Min, et al. Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase. Mol Cell. 2012 Jun 29;46(6):771-83. [Content Brief]

[15]. Bing Hao, et al. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases. Mol Cell. 2007 Apr 13;26(1):131-43. [Content Brief]

[16]. David M Duda, et al. Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface. Mol Cell. 2012 Aug 10;47(3):371-82. [Content Brief]

[17]. Junghui Koo, et al. Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation. J Biol Chem. 2015 May 29;290(22):14120-9. [Content Brief]

[18]. Maryna Gorelik, et al. Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3527-32. [Content Brief]