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Familial progressive hyperpigmentation

Definition:

Familial progressive hyperpigmentation is a dominantly inherited genodermatosis, in which patches of hyperpigmentation in the skin are present at birth. Increased number and average size of melanin granules in cells of pigmented area are the features of this disease.

References:

[1]. Mustapha Amyere, et al. KITLG mutations cause familial progressive hyper- and hypopigmentation. J Invest Dermatol. 2011 Jun;131(6):1234-9. [Content Brief]

[2]. Thierry Passeron, et al. Genetic disorders of pigmentation. Clin Dermatol. 2005 Jan-Feb;23(1):56-67. [Content Brief]

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