Fas-binding factor 1

Definition:

Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis.

References:

[1]. Barbara E Tanos, et al. Centriole distal appendages promote membrane docking, leading to cilia initiation. Genes Dev. 2013 Jan 15;27(2):163-8. [Content Brief]

[2]. Masahiko Sugimoto, et al. The keratin-binding protein Albatross regulates polarization of epithelial cells. J Cell Biol. 2008 Oct 6;183(1):19-28. [Content Brief]

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