FAST kinase domain-containing protein 1, mitochondrial

Definition:

Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity.

References:

[1]. Shuo Han, et al. Proximity Biotinylation as a Method for Mapping Proteins Associated with mtDNA in Living Cells. Cell Chem Biol. 2017 Mar 16;24(3):404-414. [Content Brief]

[2]. Erik Boehm, et al. FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain. Nucleic Acids Res. 2017 Jun 2;45(10):6135-6146. [Content Brief]

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