FERM domain-containing protein 4A

Definition:

Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling.

References:

[1]. Xu Yan, et al. FRMD4A-cytohesin signaling modulates the cellular release of tau. J Cell Sci. 2016 May 15;129(10):2003-15. [Content Brief]

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