Fletcher factor deficiency

Definition:

Fletcher factor deficiency, also called Prekallikrein deficiency, is an autosomal recessive heterozygous disorder of coagulation that is caused by defects in KLKB1. Although the patients had no abnormal bleeding tendency, their blood showed much prolonged activated partial thromboplastin time and delayed thromboplastin generation but normal prothrombin time.

References:

[1]. Antonio Girolami, et al. Congenital prekallikrein deficiency. Expert Rev Hematol. 2010 Dec;3(6):685-95. [Content Brief]

[2]. M V Ragni, et al. Prekallikrein (Fletcher factor) deficiency in clinical disease states. Thromb Res. 1980 Apr;18(1-2):45-54. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.