FXYD domain-containing ion transport regulator 5

Definition:

Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis.

References:

[1]. Yoshinori Ino, et al. Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):365-70. [Content Brief]

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