G protein-activated inward rectifier potassium channel 4
Definition:
References:
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[1]. Amalia Sertedaki, et al. Functional characterization of two novel germline mutations of the KCNJ5 gene in hypertensive patients without primary aldosteronism but with ACTH-dependent aldosterone hypersecretion. Clin Endocrinol (Oxf). 2016 Dec;85(6):845-851. [Content Brief]
[2]. Kenji Oki, et al. Potassium channel mutant KCNJ5 T158A expression in HAC-15 cells increases aldosterone synthesis. Endocrinology. 2012 Apr;153(4):1774-82. [Content Brief]
[3]. Namita G Hattangady, et al. Mutated KCNJ5 activates the acute and chronic regulatory steps in aldosterone production. J Mol Endocrinol. 2016 Jul;57(1):1-11. [Content Brief]
[4]. Silvia Monticone, et al. a Novel Y152C KCNJ5 mutation responsible for familial hyperaldosteronism type III. J Clin Endocrinol Metab. 2013 Nov;98(11):E1861-5. [Content Brief]
[5]. Evangelia Charmandari, et al. A novel point mutation in the KCNJ5 gene causing primary hyperaldosteronism and early-onset autosomal dominant hypertension. J Clin Endocrinol Metab. 2012 Aug;97(8):E1532-9. [Content Brief]
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