Galactose-3-O-sulfotransferase 3

Definition:

Transfers a sulfate to position 3 of non-reducing beta-galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha-1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha-1,4)GlcNAc.

References:

[1]. A Suzuki, et al. Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans. J Biol Chem. 2001 Jun 29;276(26):24388-95. [Content Brief]

[2]. F M El-Fasakhany, et al. A novel human Gal-3-O-sulfotransferase: molecular cloning, characterization, and its implications in biosynthesis of (SO(4)-3)Galbeta1-4(Fucalpha1-3)GlcNAc. J Biol Chem. 2001 Jul 20;276(29):26988-94. [Content Brief]

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