GAS2-like protein 1

Definition:

Involved in the cross-linking of microtubules and microfilaments. Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers.

References:

[1]. Matthew J Stroud, et al. GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins. J Cell Sci. 2014 Jun 15;127(Pt 12):2672-82. [Content Brief]

[2]. Dmitri Goriounov, et al. Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules. J Cell Sci. 2003 Mar 15;116(Pt 6):1045-58. [Content Brief]

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