GDNF-inducible zinc finger protein 1

Definition:

Transcriptional repressor that binds the GZF1 responsive element (GRE) (consensus: 5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression.

References:

[1]. Naoyuki Fukuda, et al. Identification of a novel glial cell line-derived neurotrophic factor-inducible gene required for renal branching morphogenesis. J Biol Chem. 2003 Dec 12;278(50):50386-92. [Content Brief]

[2]. Takatoshi Morinaga, et al. GDNF-inducible zinc finger protein 1 is a sequence-specific transcriptional repressor that binds to the HOXA10 gene regulatory region. Nucleic Acids Res. 2005 Jul 26;33(13):4191-201. [Content Brief]

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