GDP-fucose transporter 1

Definition:

Antiporter specific for GDP-l-fucose and depending on the concomitant reverse transport of GMP. Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.

References:

[1]. K Lühn, et al. The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter. Nat Genet. 2001 May;28(1):69-72. [Content Brief]

[2]. Karin Förster-Fromme, et al. Functional expression of a human GDP-L-fucose transporter in Escherichia coli. Biotechnol Lett. 2017 Feb;39(2):219-226. [Content Brief]

[3]. T Lübke, et al. Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. Nat Genet. 2001 May;28(1):73-6. [Content Brief]

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