Geminin
Definition:
References:
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[1]. T J McGarry, et al. Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell. 1998 Jun 12;93(6):1043-53. [Content Brief]
[2]. Bo Zhou, et al. Structural basis for homeodomain recognition by the cell-cycle regulator Geminin. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8931-6. [Content Brief]
[3]. Benoit Miotto, et al. HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin. Mol Cell. 2010 Jan 15;37(1):57-66. [Content Brief]
[4]. Nozomi Sugimoto, et al. Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding. J Biol Chem. 2004 May 7;279(19):19691-7. [Content Brief]
[5]. Christophe Caillat, et al. The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing. J Biol Chem. 2013 Nov 1;288(44):31624-34. [Content Brief]