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Glanders

Definition:

Glanders is an infectious disease of equines that can be transmitted to humans. It is usually an occupational disease, affecting individuals in contact with infected animals such as veterinarians, grooms, and farmers. The causative agent of glanders is Burkholderia mallei, a gram-negative aerobic bacterium. In equines and humans, B. mallei infection can present as either nasal-pulmonary infections (glanders) or cutaneous infections (farcy).

References:

[1]. David M Waag, et al. Humoral immune responses in a human case of glanders. Clin Vaccine Immunol. 2012 May;19(5):814-6. [Content Brief]

[2]. Edouard E Galyov, et al. Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis. Annu Rev Microbiol. 2010;64:495-517. [Content Brief]

[3]. Jacob Gilad, et al. Burkholderia mallei and Burkholderia pseudomallei: the causative micro-organisms of glanders and melioidosis. Recent Pat Antiinfect Drug Discov. 2007 Nov;2(3):233-41. [Content Brief]

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