Glutamate--cysteine ligase catalytic subunit

Definition:

Catalyzes the ATP-dependent ligation of L-glutamate and L-cysteine and participates in the first and rate-limiting step in glutathione biosynthesis.

References:

[1]. I Misra, et al. Expression and purification of human gamma-glutamylcysteine synthetase. Protein Expr Purif. 1998 Jul;13(2):268-76. [Content Brief]

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