Glutathione S-transferase Mu 2

Definition:

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Participates in the formation of novel hepoxilin regioisomers.

References:

[1]. Asa Brunnström, et al. Biosynthesis of 14,15-hepoxilins in human l1236 Hodgkin lymphoma cells and eosinophils. Lipids. 2011 Jan;46(1):69-79. [Content Brief]

[2]. Malena A Norrgård, et al. Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution. Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):4876-81. [Content Brief]

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