Glutathione-specific gamma-glutamylcyclotransferase 2

Definition:

Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

References:

[1]. Amandeep Kaur, et al. ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione. J Biol Chem. 2017 Jan 13;292(2):638-651. [Content Brief]

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