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Granulibacter infection

Definition:

Granulibacter is a gram-negative acetic acid bacterium that is recently reported to be a human opportunistic pathogen. Granulibacter has been isolated from patients with chronic granulomatous disease, in which phagocytes are not able to produce bactericidal superoxide anions. Bacteremia has also been observed in a non-immunocompromised patient with a history of intravenous drug abuse.

References:

[1]. David E Greenberg, et al. A novel bacterium associated with lymphadenitis in a patient with chronic granulomatous disease. PLoS Pathog. 2006 Apr;2(4):e28. [Content Brief]

[2]. David E Greenberg, et al. Genome sequence analysis of the emerging human pathogenic acetic acid bacterium Granulibacter bethesdensis. J Bacteriol. 2007 Dec;189(23):8727-36. [Content Brief]

[3]. David E Greenberg, et al. Granulibacter bethesdensis gen. nov., sp. nov., a distinctive pathogenic acetic acid bacterium in the family Acetobacteraceae. Int J Syst Evol Microbiol. 2006 Nov;56(Pt 11):2609-2616. [Content Brief]

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