Growth/differentiation factor 15
Definition:
References:
-
[1]. Paul J Emmerson, et al. The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL. Nat Med. 2017 Oct;23(10):1215-1219. [Content Brief]
[2]. Linda Yang, et al. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand. Nat Med. 2017 Oct;23(10):1158-1166. [Content Brief]
[3]. Yumei Xiong, et al. Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys. Sci Transl Med. 2017 Oct 18;9(412):eaan8732. [Content Brief]
[4]. Jer-Yuan Hsu, et al. Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15. Nature. 2017 Oct 12;550(7675):255-259. [Content Brief]
[5]. Vicky Wang-Wei Tsai, et al. TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator. PLoS One. 2013;8(2):e55174. [Content Brief]
[6]. Shannon E Mullican, et al. GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates. Nat Med. 2017 Oct;23(10):1150-1157. [Content Brief]
Molarity Calculator
Dilution Calculator
