GrpE protein homolog 1, mitochondrial

Definition:

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.

References:

[1]. A A Choglay, et al. Identification and characterization of a human mitochondrial homologue of the bacterial co-chaperone GrpE. Gene. 2001 Apr 4;267(1):125-34. [Content Brief]

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