Head and neck squamous cell carcinoma

Definition:

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer in the world, affecting the pharynx, larynx and oral cavity. It is well known that smoking and alcohol abuse are major risk factors for HNSCC. Additionally, human papillomavirus infection is another implicated risk factor. Although lifestyle factors account for the majority of HNSCCs, genetic alterations will cause some individuals to be more sensitive to these environmental factors.

References:

[1]. Rana Adnan Tahir, et al. Tumor necrosis factor receptor superfamily 10B (TNFRSF10B): an insight from structure modeling to virtual screening for designing drug against head and neck cancer. Theor Biol Med Model. 2013 Jun 1;10:38. [Content Brief]

[2]. Xiaohan Li, et al. ING Genes Work as Tumor Suppressor Genes in the Carcinogenesis of Head and Neck Squamous Cell Carcinoma. J Oncol. 2011;2011:963614. [Content Brief]

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