Hypoxanthine guanine phosphoribosyltransferase (HGPRT)

Definition:

Hypoxanthine guanine phosphoribosyltransferase (HGPRT) is a purine salvage enzyme that catalyses the conversion of hypoxanthine and guanine to their respective mononucleotides.

References:

[1]. Sculley DG, et al. A review of the molecular basis of hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency. Hum Genet. 1992 Nov;90(3):195-207. [Content Brief]

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