Inhibitor of apoptosis (IAP) protein

Definition:

Inhibitor of apoptosis proteins (IAPs) are a family of proteins that act to promote cell survival. IAPs are considered a promising therapeutic target for cancer treatment, based on the role of IAPs in resistance to apoptosis, tumour progression and poor patient prognosis.

References:

[1]. Michie J, et al. The Immuno-Modulatory Effects of Inhibitor of Apoptosis Protein Antagonists in Cancer Immunotherapy. Cells. 2020 Jan 14;9(1):207. [Content Brief]

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