Integral membrane protein GPR137

Definition:

Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy.; May activate Wnt/beta-catenin signaling to modulate epithelial cell function.

References:

[1]. Lin Gan, et al. The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity. Nat Cell Biol. 2019 May;21(5):614-626. [Content Brief]

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