Intraflagellar transport protein 88 homolog

Definition:

Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.

References:

[1]. Elena N Pugacheva, et al. HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell. 2007 Jun 29;129(7):1351-63. [Content Brief]

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