Lactose intolerance, adult type

Definition:

Lactose intolerance, adult type is a common condition resulting from the physiological decline in activity of the lactase phlorizin hydrolase (LPH) in intestinal cells after weaning. In a minority of adults, high levels of lactase activity persist in adulthood. Several lactase persistence alleles in the MCM6 gene have been reported.

References:

[1]. Lynne C Olds, et al. Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element. Hum Mol Genet. 2003 Sep 15;12(18):2333-40. [Content Brief]

[2]. Nabil Sabri Enattah, et al. Identification of a variant associated with adult-type hypolactasia. Nat Genet. 2002 Feb;30(2):233-7. [Content Brief]

[3]. Rejane Mattar, et al. Lactose intolerance: diagnosis, genetic, and clinical factors. Clin Exp Gastroenterol. 2012;5:113-21. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.