Lactoylglutathione lyase
Definition:
References:
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[1]. Gerd Birkenmeier, et al. Posttranslational modification of human glyoxalase 1 indicates redox-dependent regulation. PLoS One. 2010 Apr 29;5(4):e10399. [Content Brief]
[2]. M Ridderström, et al. Involvement of an active-site Zn2+ ligand in the catalytic mechanism of human glyoxalase I. J Biol Chem. 1998 Aug 21;273(34):21623-8. [Content Brief]
[3]. Takashi Chiba, et al. Design and evaluation of azaindole-substituted N-hydroxypyridones as glyoxalase I inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7486-9. [Content Brief]
[4]. Virginie de Hemptinne, et al. Phosphorylation on Thr-106 and NO-modification of glyoxalase I suppress the TNF-induced transcriptional activity of NF-kappaB. Mol Cell Biochem. 2009 May;325(1-2):169-78. [Content Brief]