Large subunit GTPase 1 homolog

Definition:

GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable).

References:

[1]. Emmanuel G Reynaud, et al. Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization. BMC Biol. 2005 Oct 7;3:21. [Content Brief]

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