Leptin receptor overlapping transcript-like 1

Definition:

Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.

References:

[1]. Thierry Touvier, et al. LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice. J Clin Invest. 2009 Dec;119(12):3830-8. [Content Brief]

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