Leucine-rich repeat-containing protein 49

Definition:

Subunit of the tubulin polyglutamylase complex (TPGC). The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility.

References:

[1]. Lei Wang, et al. Regulators of tubulin polyglutamylation control nuclear shape and cilium disassembly by balancing microtubule and actin assembly. Cell Res. 2022 Feb;32(2):190-209. [Content Brief]

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